Protein family
POU class 4 homeobox 1 |
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Identifiers |
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Symbol | POU4F1 |
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Alt. symbols | BRN3A |
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NCBI gene | 5457 |
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HGNC | 9218 |
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OMIM | 601632 |
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RefSeq | NM_006237 |
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UniProt | Q01851 |
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Other data |
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Locus | Chr. 13 q31.1 |
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Search for |
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Structures | Swiss-model |
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Domains | InterPro |
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POU class 4 homeobox 2 |
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Identifiers |
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Symbol | POU4F2 |
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Alt. symbols | BRN3B |
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NCBI gene | 5458 |
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HGNC | 9219 |
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OMIM | 113725 |
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RefSeq | NM_004575 |
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UniProt | Q12837 |
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Other data |
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Locus | Chr. 4 q31.22 |
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Search for |
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Structures | Swiss-model |
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Domains | InterPro |
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POU class 4 homeobox 3 |
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Identifiers |
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Symbol | POU4F3 |
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Alt. symbols | BRN3C, DFNA15 |
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NCBI gene | 5459 |
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HGNC | 9220 |
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OMIM | 602460 |
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RefSeq | NM_002700 |
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UniProt | Q15319 |
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Other data |
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Locus | Chr. 5 q32 |
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Search for |
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Structures | Swiss-model |
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Domains | InterPro |
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BRN-3 is a group of related transcription factors in the POU family.[1] They are also known as class 4 POU domain homeobox proteins.
There are three BRN-3 proteins encoded by the following genes:
Nomenclature
The BRN or Brn prefix is an abbreviation for "brain"; the longer name is "Brain-specific homeobox". The name of the group may also be abbreviated as POU4, Pou4, POU IV, or POU-IV.
References
- ^ Xiang M, Zhou L, Macke JP, Yoshioka T, Hendry SH, Eddy RL, Shows TB, Nathans J (1995). "The Brn-3 family of POU-domain factors: primary structure, binding specificity, and expression in subsets of retinal ganglion cells and somatosensory neurons". J. Neurosci. 15 (7 Pt 1): 4762–85. doi:10.1523/JNEUROSCI.15-07-04762.1995. PMC 6577904. PMID 7623109.
External links
(1) Basic domains |
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(1.1) Basic leucine zipper (bZIP) | |
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(1.2) Basic helix-loop-helix (bHLH) | Group A | |
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Group B | |
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Group C bHLH-PAS | |
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Group D | |
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Group E | |
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Group F bHLH-COE | |
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(1.3) bHLH-ZIP | |
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(1.4) NF-1 | |
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(1.5) RF-X | |
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(1.6) Basic helix-span-helix (bHSH) | |
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(2) Zinc finger DNA-binding domains |
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(2.1) Nuclear receptor (Cys4) | subfamily 1 | |
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subfamily 2 | |
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subfamily 3 | |
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subfamily 4 | |
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subfamily 5 | |
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subfamily 6 | |
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subfamily 0 | |
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(2.2) Other Cys4 | |
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(2.3) Cys2His2 | |
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(2.4) Cys6 | |
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(2.5) Alternating composition | |
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(2.6) WRKY | |
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(4) β-Scaffold factors with minor groove contacts |
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(0) Other transcription factors |
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see also transcription factor/coregulator deficiencies |
| This article on a gene on human chromosome 13 is a stub. You can help Wikipedia by expanding it. |