P2RX2 |
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Identifiers |
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Aliases | P2RX2, DFNA41, P2X2, purinergic receptor P2X 2 |
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External IDs | OMIM: 600844; MGI: 2665170; HomoloGene: 14251; GeneCards: P2RX2; OMA:P2RX2 - orthologs |
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Gene location (Human) |
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| Chr. | Chromosome 12 (human)[1] |
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| Band | 12q24.33 | Start | 132,618,776 bp[1] |
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End | 132,622,388 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 5 (mouse)[2] |
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| Band | 5|5 F | Start | 110,487,678 bp[2] |
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End | 110,491,078 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - gastric mucosa
- right lung
- right uterine tube
- prostate
- caput epididymis
- tail of epididymis
- corpus epididymis
- hippocampus proper
- spleen
- upper lobe of left lung
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| Top expressed in | - vestibular membrane of cochlear duct
- otolith organ
- utricle
- seminiferous tubule
- spermatocyte
- ganglion of vagus nerve
- spermatid
- vestibular sensory epithelium
- cochlea
- embryo
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| More reference expression data |
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BioGPS |
| More reference expression data |
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Gene ontology |
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Molecular function | - purinergic nucleotide receptor activity
- extracellularly ATP-gated cation channel activity
- ion channel activity
- ligand-gated ion channel activity
- identical protein binding
- ATP binding
- ATP-gated ion channel activity
| Cellular component | - integral component of membrane
- membrane
- receptor complex
- integral component of nuclear inner membrane
- integral component of plasma membrane
- intracellular anatomical structure
- apical plasma membrane
- plasma membrane
- postsynapse
- neuronal cell body
| Biological process | - peristalsis
- response to ATP
- positive regulation of calcium-mediated signaling
- response to hypoxia
- positive regulation of calcium ion transport into cytosol
- urinary bladder smooth muscle contraction
- hearing
- ion transport
- response to organic substance
- cation transmembrane transport
- neuromuscular synaptic transmission
- behavioral response to pain
- neuromuscular junction development
- skeletal muscle fiber development
- detection of hypoxic conditions in blood by carotid body chemoreceptor signaling
- protein homooligomerization
- response to carbohydrate
- sensory perception of taste
- chemical synaptic transmission
- blood coagulation
- purinergic nucleotide receptor signaling pathway
- excitatory postsynaptic potential
- response to ischemia
- cation transport
- ion transmembrane transport
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | NM_001282164 NM_001282165 NM_012226 NM_016318 NM_170682
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NM_170683 NM_174872 NM_174873 |
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NM_001164833 NM_001164834 NM_153400 NM_001310700 NM_001310701 |
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RefSeq (protein) | NP_001269093 NP_001269094 NP_036358 NP_057402 NP_733782
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NP_733783 NP_777361 NP_777362 |
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NP_001158305 NP_001158306 NP_001297629 NP_001297630 NP_700449 |
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Location (UCSC) | Chr 12: 132.62 – 132.62 Mb | Chr 5: 110.49 – 110.49 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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