GPR17
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G protein-spregnuti receptor 17 | |||||||||||
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Identifikatori | |||||||||||
Simboli | GPR17; DKFZp686M18273 | ||||||||||
Vanjski ID | OMIM: 603071 MGI: 3584514 HomoloGene: 83191 IUPHAR: GPR17 GeneCards: GPR17 Gene | ||||||||||
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Pregled RNK izražavanja | |||||||||||
podaci | |||||||||||
Ortolozi | |||||||||||
Vrsta | Čovek | Miš | |||||||||
Entrez | 2840 | 574402 | |||||||||
Ensembl | ENSG00000144230 | ENSMUSG00000052229 | |||||||||
UniProt | Q13304 | n/a | |||||||||
RefSeq (mRNA) | NM_005291 | NM_001025381 | |||||||||
RefSeq (protein) | NP_005282 | NP_001020552 | |||||||||
Lokacija (UCSC) | Chr 2: 128.12 - 128.13 Mb | Chr 18: 32.09 - 32.09 Mb | |||||||||
PubMed pretraga | [1] | [2] |
GPR17, Uracil nukleotidni/cisteinil leukotrienski receptor, je protein koji je kod čoveka kodiran GPR17 genom.[1][2]
Povezano
- Leukotrien
Literatura
Dodatna literatura
- Macrez-Leprêtre N, Kalkbrenner F, Morel JL, et al. (1997). „G protein heterotrimer Galpha13beta1gamma3 couples the angiotensin AT1A receptor to increases in cytoplasmic Ca2+ in rat portal vein myocytes.”. J. Biol. Chem. 272 (15): 10095–102. DOI:10.1074/jbc.272.15.10095. PMID 9092554.
- Bläsius R, Weber RG, Lichter P, Ogilvie A (1998). „A novel orphan G protein-coupled receptor primarily expressed in the brain is localized on human chromosomal band 2q21.”. J. Neurochem. 70 (4): 1357–65. DOI:10.1046/j.1471-4159.1998.70041357.x. PMID 9523551.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). „Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. DOI:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). „The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).”. Genome Res. 14 (10B): 2121–7. DOI:10.1101/gr.2596504. PMC 528928. PMID 15489334.
- Rual JF, Venkatesan K, Hao T, et al. (2005). „Towards a proteome-scale map of the human protein-protein interaction network.”. Nature 437 (7062): 1173–8. DOI:10.1038/nature04209. PMID 16189514.
- Ciana P, Fumagalli M, Trincavelli ML, et al. (2006). „The orphan receptor GPR17 identified as a new dual uracil nucleotides/cysteinyl-leukotrienes receptor.”. EMBO J. 25 (19): 4615–27. DOI:10.1038/sj.emboj.7601341. PMC 1589991. PMID 16990797.
- M. Kandhavelu, M. P. Abbracchio, P. Angeli, M. Buccioni, D. Dal Ben, C. Lammi, D. Lecca, G. Marucci, G. Cristalli. “Site directed mutagenesis of GPR17 receptor” 16th Camerino-Noordwijkerhout Symposium “An Overview on Receptor Chemistry, Camerino, September 9-13,P28, 2007.http://www.unicam.it/farmacia/symposium/abstracts.htm
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Drugi | Moždano specifični angiogenezni inhibitor (1, 2, 3) • Cadherin (1, 2, 3) • Kalcitonin • CALCRL • CD97 • Kortikotropin-oslobađajući hormon (1, 2) • EMR (1, 2, 3) • Glukagon (GR, GIPR, GLP1R, GLP2R) • Hormon rasta oslobađajući hormon • PACAPR1 • GPR • Latrofilin (1, 2, 3, ELTD1) • Metuselah-slični proteini • Paratiroidni hormon (1, 2) • Sekretin • Vazoaktivni intestinalni peptid (1, 2) |
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glutamat / feromon
Drugi |
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Frizzled / Zaglađeni
Uvojiti | |
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Zaglađeni |
B trdu: peptidi (nrpl/grfl/cytl/horl), receptori (lgic, enzr, gprc, igsr, intg, nrpr/grfr/cytr), itra (adap, gbpr, mapk), calc, lipd, signalni putevi (hedp, wntp, tgfp+mapp, notp, jakp, fsap, hipp, tlrp)