HLA-C
Major histocompatibility complex, class I, C 主要组织相容性抗原复合物,第一类,C | |||||||||||||
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Illustration of an HLA-C showing the HLA-B 'alpha' chain, ?2-Microglobulin, and the end of a peptide bound in the binding cleft. | |||||||||||||
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标识 | |||||||||||||
代号 | HLA-C; D6S204; HLA-JY3; HLC-C; PSORS1 | ||||||||||||
扩展标识 | 遗传学:142840 同源基因:133080 GeneCards: HLA-C Gene | ||||||||||||
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RNA表达模式 | |||||||||||||
更多表达数据 | |||||||||||||
直系同源体 | |||||||||||||
物种 | 人类 | 小鼠 | |||||||||||
Entrez | 3107 | 14964 | |||||||||||
Ensembl | ENSG00000204525 | ENSMUSG00000073411 | |||||||||||
UniProt | P10321 | P01899 | |||||||||||
mRNA序列 | NM_001243042 | NM_010380.3 | |||||||||||
蛋白序列 | NP_001229971 | NP_034510.3 | |||||||||||
基因位置 | Chr 6: 31.24 – 31.24 Mb | Chr 17: 35.26 – 35.27 Mb | |||||||||||
PubMed查询 | [1] | [2] | |||||||||||
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HLA-C是人類白細胞抗原(HLA)的一个基因座,位于6号染色体上。成熟的HLA-C蛋白会与β2微球蛋白组成异二聚体,作为一个受体锚定在细胞表面。
参考文献
延伸阅读
- Geyer M, Fackler OT, Peterlin BM. Structure--function relationships in HIV-1 Nef.. EMBO Rep. 2001, 2 (7): 580–5. PMC 1083955 . PMID 11463741. doi:10.1093/embo-reports/kve141.
- Greenway AL, Holloway G, McPhee DA; et al. HIV-1 Nef control of cell signalling molecules: multiple strategies to promote virus replication.. J. Biosci. 2004, 28 (3): 323–35. PMID 12734410. doi:10.1007/BF02970151. 引文格式1维护:显式使用等标签 (link)
- Bénichou S, Benmerah A. [The HIV nef and the Kaposi-sarcoma-associated virus K3/K5 proteins: "parasites"of the endocytosis pathway]. Med Sci (Paris). 2003, 19 (1): 100–6. PMID 12836198. doi:10.1051/medsci/2003191100.
- Leavitt SA, SchOn A, Klein JC; et al. Interactions of HIV-1 proteins gp120 and Nef with cellular partners define a novel allosteric paradigm.. Curr. Protein Pept. Sci. 2004, 5 (1): 1–8. PMID 14965316. doi:10.2174/1389203043486955. 引文格式1维护:显式使用等标签 (link)
- Tolstrup M, Ostergaard L, Laursen AL; et al. HIV/SIV escape from immune surveillance: focus on Nef.. Curr. HIV Res. 2004, 2 (2): 141–51. PMID 15078178. doi:10.2174/1570162043484924. 引文格式1维护:显式使用等标签 (link)
- Joseph AM, Kumar M, Mitra D. Nef: "necessary and enforcing factor" in HIV infection.. Curr. HIV Res. 2005, 3 (1): 87–94. PMID 15638726. doi:10.2174/1570162052773013.
- Anderson JL, Hope TJ. HIV accessory proteins and surviving the host cell.. Current HIV/AIDS reports. 2005, 1 (1): 47–53. PMID 16091223. doi:10.1007/s11904-004-0007-x.
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外部链接
- Molecular Anthropology Yahoo Group(页面存档备份,存于互联网档案馆)
- HLA Allele and Haplotype Frequency Database(页面存档备份,存于互联网档案馆)
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