Mizolastine
Chemical compound
- R06AX25 (WHO)
- UK: POM (Prescription only)
- 2-[{1-[1-(4-Fluorobenzyl)-1H-benzimidazol-2-yl]piperidin-4-yl}(methyl)amino]pyrimidin-4(1H)-one
- 108612-45-9 Y
- 65906
- 59315 N
- 244O1F90NA
- D01117 Y
- ChEMBL94454 N
- DTXSID5046801
- Interactive image
- CN(C1CCN(CC1)C2=NC3=CC=CC=C3N2CC4=CC=C(C=C4)F)C5=NC=CC(=O)N5
InChI
- InChI=1S/C24H25FN6O/c1-29(23-26-13-10-22(32)28-23)19-11-14-30(15-12-19)24-27-20-4-2-3-5-21(20)31(24)16-17-6-8-18(25)9-7-17/h2-10,13,19H,11-12,14-16H2,1H3,(H,26,28,32) N
- Key:PVLJETXTTWAYEW-UHFFFAOYSA-N N
Mizolastine (Mizollen) is a once-daily, non-sedating antihistamine. It blocks H1 receptors and is commonly fast-acting.[1] It does not prevent the actual release of histamine from mast cells, it only prevents histamine from binding to receptors. Side effects can include dry mouth and throat.[2]
References
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Antihistamines (R06)
- Astemizole
- Azelastine
- Bilastine
- Emedastine
- Mizolastine
- Talastine
- Diarylmethoxyalkylamines: Bromazine (bromodiphenhydramine)
- Carbinoxamine
- Chlorphenoxamine
- Clemastine
- Diphenhydramine (+naproxen)
- Diphenylpyraline
- Doxylamine
- Ebastine
- Orphenadrine
- Diphenylmethylpiperazines: Buclizine
- Cetirizine
- Chlorcyclizine
- Cinnarizine
- Cyclizine
- Etodroxizine
- Hydroxyzine
- Meclizine
- Oxatomide
- Phenylpyridinylpropanamines: Brompheniramine
- Chlorphenamine
- Dexbrompheniramine (+pseudoephedrine)
- Dexchlorpheniramine (+betamethasone)
- Pheniramine
- Phenylpiperazines: Antidepressants (e.g., trazodone)
- Phenbenzamine
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