FCGR2B |
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Наявні структури |
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PDB | Пошук ортологів: PDBe RCSB | Список кодів PDB | 2FCB, 3WJJ,%%s3WJL | | |
Ідентифікатори |
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Символи | FCGR2B, CD32, CD32B, FCG2, FCGR2, IGFR2, Fc fragment of IgG receptor IIb, FcRII-c, FCGR2C |
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Зовнішні ІД | OMIM: 604590 MGI: 95499 HomoloGene: 2974 GeneCards: FCGR2B |
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Онтологія гена |
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Молекулярна функція | • GO:0001948, GO:0016582 protein binding • IgG binding • amyloid-beta binding • low-affinity IgG receptor activity • GO:0032403 protein-containing complex binding • transmembrane signaling receptor activity |
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Клітинна компонента | • integral component of membrane • клітинна мембрана • мембрана • integral component of plasma membrane • external side of plasma membrane • dendritic spine • cell body • цитоплазма |
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Біологічний процес | • GO:0022415 viral process • GO:0046730, GO:0046737, GO:0046738, GO:0046736 імунна відповідь • GO:0072468 сигнальна трансдукція • regulation of immune response • negative regulation of type I hypersensitivity • negative regulation of antibody-dependent cellular cytotoxicity • follicular dendritic cell activation • mature B cell differentiation involved in immune response • follicular B cell differentiation • immune complex clearance by monocytes and macrophages • negative regulation of dendritic cell antigen processing and presentation • regulation of B cell antigen processing and presentation • negative regulation of immunoglobulin production • regulation of adaptive immune response • negative regulation of acute inflammatory response to antigenic stimulus • positive regulation of humoral immune response • negative regulation of humoral immune response mediated by circulating immunoglobulin • рецептор-опосередкований ендоцитоз • phagocytosis, engulfment • defense response • inflammatory response • response to bacterium • regulation of signaling receptor activity • immunoglobulin mediated immune response • antigen processing and presentation of exogenous peptide antigen via MHC class II • cerebellum development • negative regulation of B cell proliferation • negative regulation of interleukin-10 production • Fc-gamma receptor signaling pathway involved in phagocytosis • negative regulation of macrophage activation • negative regulation of cytotoxic T cell degranulation • regulation of innate immune response • mast cell activation • positive regulation of JNK cascade • negative regulation of phagocytosis • positive regulation of phagocytosis • negative regulation of immune response • negative regulation of B cell receptor signaling pathway • negative regulation of B cell activation • cellular response to molecule of bacterial origin • regulation of immune complex clearance by monocytes and macrophages • positive regulation of neuron death • negative regulation of neutrophil activation • regulation of dendritic spine maintenance • cellular response to amyloid-beta • positive regulation of response to endoplasmic reticulum stress • negative regulation of dendritic cell differentiation |
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Джерела:Amigo / QuickGO | |
Ортологи |
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Види | Людина | Миша |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (мРНК) | | NM_001002273 NM_001002274 NM_001002275 NM_001190828 NM_004001 |
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RefSeq (білок) | NP_001002273 NP_001002274 NP_001002275 NP_001177757 NP_003992
| NP_963857 |
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Локус (UCSC) | Хр. 1: 161.66 – 161.68 Mb | Хр. 1: 170.79 – 170.8 Mb |
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PubMed search | [1] | [2] |
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Вікідані |
Див./Ред. для людей | Див./Ред. для мишей |
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